Pras et al reported a score for describing the severity of Familial Mediterranean Fever (FMF). The authors are from Sheba Medical Center in Israel and the National Institute of Arthritis and Musculoskeletal and Skin Diseases.
Patient selection: patient with FMF
Parameters:
(1) age of onset in years
(2) number of attacks per month
(3) arthritis
(4) erysipelas-like erythema
(5) amyloidosis
(6) dose of colchicine
Parameter
Finding
Points
age of onset
< 6 years
4
6 to 10 years
3
11 to 20 years
2
21 to 31 years
1
> 31 years
0
number of attacks
< 1 per month
1
1 or 2 per month
2
> 2 per month
3
arthritis
none
0
acute
2
protracted
3
erysipelas-like erythema
no
0
yes
2
amyloidosis
no
0
yes
3
dose of colchicine
1 mg per day
1
1.5 mg per day
2
2 mg per day
3
> 2 mg per day
4
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 2
• maximum score: 19
• The higher the score the more severe the disease.
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