Pradjatmo et al reported a score for predicting the risk of malignancy in a hydatidiform mole. The authors are from Universitas Gadjah Mada in Jogjakarta, Indonesia.
Patient selection: hydatidiform mole
Parameters:
(1) age of the patient in years
(2) gestational age in weeks
(3) uterine size relative to gestational age
(4) histopathologic Grade from I to III
Parameter
Finding
Points
age in years
<= 35 years
0
> 35 years
5
gestational age in weeks
< 12 weeks
0
>= 12 weeks
26
uterine size
smaller than or appropriate for gestational age
0
greater than appropriate
21
histopathologic grade
I
0
II or III
3
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 55
• A score >= 31 has a sensitivity of 0.82 and specificity of 0.82 for malignancy.
Performance:
• A ROC curve is shown but the area under the curve is not reported.
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