Score of Ouyang et al for Differentiated Tuberculosis from Non-Tubercular Pulmonary Infections in an HIV-Positive Patient with Severe Immunosuppression
Ouyang et al reported a score for distinguishing tuberculosis from other causes of pulmonary infection in a severely immunocompromised HIV-positive patient. The authors are from Chongqing Public Health Medical Center and Capital Medical University in China,
Patient selection: HIV-positive with severe immunosuppression
Parameters:
(1) fever (not specified)
(2) highest body temperature in °C during hospital stay
(3) ESR in mm per hour
(4) cervical lymphadenopathy
(5) hilar and/or mediastinal lymphadenopathy
(6) pulmonary cavity
(7) pleural effusion
(8) miliary nodules
Parameter
Finding
Transformed Value
highest body temperature
< 37.3°C
0
37.4 to 38.4°C
1
38.5 t 38.9°C
2
39.0 to 39.9°C
3
>= 40°C
4
ESR
<= 20 mm/h
0
20.1 to 49.9 mm/h
1
50 to 79.9 mm/h
2
80 to 99.9 mm/h
3
>= 100 mm/h
4
Parameters
Findings
Points
fever
no
0
yes
3.5
highest body temperature
2.5 * (value)
ESR
(value)
cervical lymphadenopathy
no
0
yes
3.5
hilar and/or mediastinal lymphadenopathy
no
0
yes
3.5
pulmonary cavity
no
0
yes
5
pleural effusion
no
0
yes
3.5
miliary nodules
no
0
yes
9.5
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 42.5
• Scores in the study ranged from 2.5 to 32 with higher scores seen in tuberculosis.
• A score > 12 is associated with tuberculosis.
• A score <= 12 indicates a cause other than tuberculosis.
Performance:
• The area under the ROC curve is 0.90.
To read more or access our algorithms and calculators, please log in or register.
