Nyberg et al developed a score for evaluating the donor of a cadaver kidney prior to transplantation. These can help to identify a kidney of marginal quality. The authors are from the Mayo Clinic and University of Minnesota.
Parameters:
(1) age of the donor in years
(2) history of hypertension in the donor
(3) creatinine clearance of the donor
(4) cause of donor's death
(5) number of HLA antigen mismatches with the recipients
|
Parameter |
Findings |
Points |
|---|---|---|
|
age of the donor |
< 30 years |
0 |
|
|
30 to 39 years |
5 |
|
|
40 to 49 years |
10 |
|
|
50 to 59 years |
15 |
|
|
60 to 69 years |
20 |
|
|
>= 70 years of age |
25 |
|
history of hypertension |
none |
0 |
|
|
<= 5 years or duration unknown |
2 |
|
|
6 to 10 years |
3 |
|
|
> 10 years |
4 |
|
creatinine clearance |
>= 100 mL/min |
0 |
|
|
75 to 99 mL/min |
2 |
|
|
50 to 74 mL/min |
3 |
|
|
< 50 mL/min |
4 |
|
cause of death |
cerebrovascular accident |
3 |
|
|
other |
0 |
|
HLA antigen mismatches |
0 |
0 |
|
|
1 or 2 |
1 |
|
|
3 or 4 |
2 |
|
|
5 or 6 |
3 |
total score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum score: 0
• maximum score: 39
• The higher the score the greater the risk of a suboptimal outcome following the transplant.
|
Total Score |
Kidney Grade |
Graft Survival at 6 Years |
|---|---|---|
|
0 to 9 |
A |
81% |
|
10 to 19 |
B |
77% |
|
20 to 29 |
C |
68% |
|
30 to 39 |
D |
62% |
Purpose: To evaluate the donor of a cadaver kidney prior to transplantation using the score of Nyberg et al.
Specialty: Nephrology, Clinical Laboratory, Surgery, general
Objective: clinical diagnosis, including family history for genetics, other testing
ICD-10: Z94.0,
