Nenclares et al reported a score for predicting overall survival following radiation therapy for a patient with metastatic spinal cord compression. The authors are from Royal Marsden NHS Trust and University Hospital 12 de Octubre in Madrid.
Parameters:
(1) age in years
(2) number of involved vertebrae
(3) ECOG status
(4) histology
Parameter
Finding
Points
age
<= 60 years
6
> 60 years
4
number vertebrae
1
5
> 1
4
ECOG
0 or 1
6
2 or 3
3
histology
favorable
7
non-favorable
3
total score =
= SUM(points for all 4 parameters)
Interpretation:
• minimum score: 14
• maximum score: 24
• A patient with a score >= 19 may benefit from long-course radiation therapy.
Score
6-Month Overall Survival
Median Survival
14 to 18
22%
2.8 months
19 to 24
69%
10 months
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