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Score of Martinez-Gimeno et al for Predicting Lymph Node Metastases in a Patient with Squamous Cell Carcinoma of the Oral Cavity

Description

Martinez-Gimeno et al developed a score for predicting the risk of cervical lymph node metastases in a patient with a squamous cell carcinoma of the oral cavity. This can help to identify a patient who may benefit from more aggressive management. the authors are from Hospital General Gregorio Maranon and Hospital Nuestra Senora de la Candelaria in Madrid, Spain.


Patient selection: squamous cell carcinoma of the oral cavity

 

Outcome: cervical lymph node metastasis

 

Parameter:

(1) T category

(2) tumor thickness in mm

(3) intravascular invasion

(4) perineural spread

(5) grade of differentiation

(6) tumor interphase (margin)

(7) inflammatory response

 

Parameter

Findings

Points

T category

T1

1

 

T2

3

 

T3

3

 

T4

5

tumor thickness

<= 3 mm

1

 

3.1 to 7 mm

3

 

> 7 mm

5

intravascular invasion

negative

1

 

positive

7

perineural spread

negative

1

 

positive

2

differentiation

good

1

 

moderate

3

 

poor

5

tumor interphase

uniform front

1

 

other

3

inflammatory response

moderate or high

1

 

none or light

3

 

total score =

= SUM(points for all 7 parameters)

 

Interpretation:

• minimum score: 7

• maximum score: 30

• The higher the score the greater the risk of lymph node metastases.

 

Total Score

Percent Metastases

7 to 12

0%

13 to 16

20%

17 to 20

64%

21 to 30

86%

 


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