Lee et al reported a score for identifying a pediatric patient at risk for life-threatening asthma. This can help to identify a patient who may require more aggressive measurement. The authors are from UNSW Sydney and Sydney Children's Hospital in Australia.
Patient selection: age 2 to 17 years of age with history of asthma
Parameters:
(1) age in years
(2) family history of asthma/atopy
(3) socioeconomic status (SES), from1 (lowest) to 5 highest
(4) number of previous hospitalizations for asthma
Parameter
Finding
Beta-Coefficient
age in years
0.109 * (years)
family history
no
0
yes
0.849
SES
lowest (SES1)
1.859
second lowest (SES2)
1.334
mid (SES3)
0.993
second highest (SES4)
0.443
highest (SES5)
0
previous hospitalizatoins
0
0
1 to 3
0.739
>= 4
2.781
value of X =
= SUM(points for all of the parameters) - 4.179
probability of severe asthma =
= 1 / (1 + EXP((-1) * X))
A score > 0.0718 was 79% sensitive and 47% specific for severe asthma.
Performance:
• The area under the ROC curve is 0.76.
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