Description

Jun et al developed a score for predicting extrahepatic metastases in a patient with an hepatocellular carcinoma following curative hepatectomy. This can help to identify a patient who may benefit from more aggressive management. The authors are from the Eastern Hepatobiliary Surgery Hospital and Second Military Medical University in Shanghai.


 

Patient selection: hepatocellular carcinoma following curative hepatectomy

 

Outcome: extrahepatic metastases (EHM)

 

Parameters:

(1) tumor size in cm

(2) capsule of the tumor

(3) microvascular invasion (MVI)

 

Parameter

Finding

Points

capsule

complete

0

 

incomplete

25

microvascular invasion

no

0

 

yes

26

 

score =

= (diameter in cm) + (points for capsule) + (points for microvascular invasion)

 

Interpretation:

• minimum score: 0

• maximum score: 72 or more (depending on the diameter of the tumor)

• The higher the score the greater the risk for extrahepatic metastases.

• A score >= 43 was associated with a higher risk for extrahepatic metastases.

 

Performance:

• The AUC for the ROC curve was 0.81 with sensitivity 90% and specificity 62%.

 


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