Haridas et al reported a simple score for predicting that a patient will have severe dengue. This is suitable for a hospital with limited resources. The authors are from Amrita Institute of Medical Sciences and Research Centre in Kerala, India.
Patient selection: adult with dengue in India
Parameters:
(1) petechiae
(2) serum ALT in U/L
(3) serum albumin in g/dL
(4) blood urea nitrogen in mg/dL
Parameter
Finding
Points
petechiae
no
0
yes
1
serum ALT
<= 40 U/L
0
> 40 U/L
1
serum albumin
>= 3.5 g/dL
0
< 3.5 g/dL
1
serum BUN
<= 40 mg/dL
0
> 40 mg/dL
1
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 4
• A score >= 2 is associated with severe dengue (100% sensitive, 96% specific)..
Performance:
• The area under the ROC curve is 0.97.
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