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Description

Haridas et al reported a simple score for predicting that a patient will have severe dengue. This is suitable for a hospital with limited resources. The authors are from Amrita Institute of Medical Sciences and Research Centre in Kerala, India.


Patient selection: adult with dengue in India

 

Parameters:

(1) petechiae

(2) serum ALT in U/L

(3) serum albumin in g/dL

(4) blood urea nitrogen in mg/dL

 

Parameter

Finding

Points

petechiae

no

0

 

yes

1

serum ALT

<= 40 U/L

0

 

> 40 U/L

1

serum albumin

>= 3.5 g/dL

0

 

< 3.5 g/dL

1

serum BUN

<= 40 mg/dL

0

 

> 40 mg/dL

1

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 4

• A score >= 2 is associated with severe dengue (100% sensitive, 96% specific)..

 

Performance:

• The area under the ROC curve is 0.97.


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