Grandi et al developed a score for staging patients with nasopharyngeal cancer. The authors are from the University of Milan.
Parameters:
(1) age in years
(2) histologic differentiation of the tumor
(3) extent of primary relative to the nasopharynx
(4) clinical lymph node involvement
|
Parameter |
Finding |
Points |
|---|---|---|
|
age in years |
<= 50 years of age |
0 |
|
|
> 50 years of age |
1 |
|
histologic differentiation |
undifferentiated |
0 |
|
|
squamous cell carcinoma |
1 |
|
extent of primary |
confined to nasopharynx |
0 |
|
|
extends beyond the nasopharynx |
1 |
|
lymph node involvement |
none clinically |
0 |
|
|
one level from the first or second levels |
1 |
|
|
both the first and second levels |
1 |
|
|
third level |
2 |
where:
• Level 1 lymph nodes are at or above the hyoid bone. Level 2 lymph nodes are between the hyoid bone and the lower margin of the thyroid cartilage. Level 3 lymph nodes are below the lower edge of the thyroid cartilage (Figure 3, page 1990).
total score =
= SUM(points for all 4 parameters)
Interpretation:
• minimum score: 0
• maximum score: 5
• The higher the score the higher the stage.
|
Total Score |
Stage |
|---|---|
|
0 |
0 |
|
1 |
1 |
|
2 |
2 |
|
3 |
3 |
|
4 or 5 |
4 |
Purpose: To evaluate a patient with a nasopharyngeal cancer using the clinical score of Grandi et al.
Specialty: Hematology Oncology, Surgery, general, Otolaryngology
Objective: risk factors, severity, prognosis, stage, complications, selection
ICD-10: C11,
