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Description

Gannon et al developed a simple score for evaluating a patient with interstitial lung disease and acute respiratory failure. This can help to identify a patient who may benefit from more aggressive management. The authors are from Columbia University in New York City.


Patient selection: acute respiratory failure in setting of interstitial lung disease

 

Outcome: in-hospital mortality and cumulative 1-year mortality

 

Parameters:

(1) sex

(2) diagnosis of idiopathic pulmonary fibrosis

(3) body mass index (BMI), in kg per square meter

(4) mechanical ventilation or extracorporeal life support

(5) able to ambulate

(6) SAPS II score

 

Parameter

Finding

Points

sex

female

0

 

male

2

diagnosis of idiopathic pulmonary fibrosis

no

0

 

yes

1

BMI

<= 25

0

 

26 to 30

1

 

31 to 35

2

 

> 35

3

mechanical ventilation or extracorporeal life support

no

0

 

yes

2

ambulation

yes

0

 

no

1

SAPS II

<= 20

0

 

21 to 30

3

 

> 30

4

 

total score =

= SUM(points for all 6 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 13

• The higher the score the greater the risk for mortality.

 

Score

Risk for Mortality

In-Hospital Mortality

Cumulative 1-Year Mortality

0 to 4

low

33%

57%

5 to 8

moderate

65%

81%

9 to 13

high

96%

96%

 

Performance:

• The area under the ROC curve was 0.73 (optimism corrected).


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