Gannon et al developed a simple score for evaluating a patient with interstitial lung disease and acute respiratory failure. This can help to identify a patient who may benefit from more aggressive management. The authors are from Columbia University in New York City.
Patient selection: acute respiratory failure in setting of interstitial lung disease
Outcome: in-hospital mortality and cumulative 1-year mortality
Parameters:
(1) sex
(2) diagnosis of idiopathic pulmonary fibrosis
(3) body mass index (BMI), in kg per square meter
(4) mechanical ventilation or extracorporeal life support
(5) able to ambulate
(6) SAPS II score
Parameter |
Finding |
Points |
sex |
female |
0 |
|
male |
2 |
diagnosis of idiopathic pulmonary fibrosis |
no |
0 |
|
yes |
1 |
BMI |
<= 25 |
0 |
|
26 to 30 |
1 |
|
31 to 35 |
2 |
|
> 35 |
3 |
mechanical ventilation or extracorporeal life support |
no |
0 |
|
yes |
2 |
ambulation |
yes |
0 |
|
no |
1 |
SAPS II |
<= 20 |
0 |
|
21 to 30 |
3 |
|
> 30 |
4 |
total score =
= SUM(points for all 6 parameters)
Interpretation:
• minimum score: 0
• maximum score: 13
• The higher the score the greater the risk for mortality.
Score |
Risk for Mortality |
In-Hospital Mortality |
Cumulative 1-Year Mortality |
0 to 4 |
low |
33% |
57% |
5 to 8 |
moderate |
65% |
81% |
9 to 13 |
high |
96% |
96% |
Performance:
• The area under the ROC curve was 0.73 (optimism corrected).
Specialty: Pulmonology, Immunology/Rheumatology