Score of Erdur et al for Risk of Thrombolysis-Associated Intracranial Hemorrhage in a Patient with an Acute Ischemic Stroke (Risk of sICH Score, RICH Score)

Description

Erdur et al reported a simple score for predicting the risk of symptomatic intracranial hemorrhage following thrombolytic therapy of an acute ischemic stroke. The authors are from Charite-Universitatsmedizin Berlin, University of Basel and Felix Platter Hospital (Basel).

Patient selection: acute ischemic stroke treated with recombinant tissue-plasminogen activator

Outcome: symptomatic intracranial hemorrhage (sICH)

Parameters:

(1) age in years

(2) NIH stroke scale

(3) blood glucose in mg/dL

(4) systolic blood pressure in mm Hg

(5) pretreatment with medium or high-dose statins

Parameter	Finding	Points
age in years	<= 80 years	0
	> 80 years	1
NIH stroke scale	0 to 4	0
	>= 5	1
blood glucose	<= 125 mg/dL	0
	> 125 mg/dL	1
systolic blood pressure	<= 155 mm Hg	0
	> 155 mm Hg	1
statin pretreatment	no	0
	yes	1

total score =

= SUM(points for all of the parameters)

Interpretation:

• minimum score: 0

• maximum score: 5

Total Score	Percent sICH
0	0%
1	1.7%
2	2.7%
3	6.3%
>= 4	8.1%

Performance:

• The area under the ROC curve was 0.72 for the derivation and 0.69 for validation cohorts.

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Score of Erdur et al for Risk of Thrombolysis-Associated Intracranial Hemorrhage in a Patient with an Acute Ischemic Stroke (Risk of sICH Score, RICH Score)

Description

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