Description

Copas et al developed a simple risk score for determining the risk of having antibodies to herpes simplex type 2 based on the patient's clinical history. The authors are from the Royal Free and University College London Medical School.


 

Parameter:

(1) gender

(2) age in years

(3) number of lifetime sexual partners

(4) genital blisters

 

Parameter

Finding

Points

gender

male

0

 

female

2

age in years

<= 24 years

0

 

25 - 29

1

 

>= 30 years

2

number of lifetime sexual partners

0

0

 

1 or 2

0

 

3 to 9

2

 

>= 10

3

genital blisters

never

0

 

once

2

 

less than once per year

3

 

1 to 3 times per year

3

 

>= 4 times per year

3

 

total score =

= SUM(points for all 4 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 10

• The higher the score the greater the risk of having serum antibodies to HSV type 2.

 

Total Score

Risk Group

Mean Prevalence HSV-2

<= 3

1 (very low)

0.7% (0.7 to 4.8)

4

2 (very low)

2% (2.0 to 7.9)

5

3 (low)

6.2% (6.2 to 16)

6

4 (moderate)

14.1% (14.1 to 28.1)

>= 7

5 (high)

47.3% (47.1 to 67.7)

 

where:

• The prevalence figures outside the parentheses in Table 3 are for blood donors. Other study groups showed higher risks in each risk group (range of values in parentheses).

 


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