Schopf-Schulz-Passarge Syndrome (SSPS) is one of the syndromes associated with ectodermal dysplasia.


Chromosome: 2q35

Gene: WNT10A


Inheritance: autosomal recessive


Clinical features:

(1) keratosis palmoplantaris (palmoplantar hyperkeratosis)

(2) cystic tumors of the eyelid

(3) hypodontia with disorders of deciduous and permanent dentition

(4) hypotrichosis with or without alopecia (trichodysplasia)

(5) nail fragility or hypoplasia (onychodystrophy)

(6) variable hyperhidrosis

(7) absence of facial dysmorphism


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