A nephropathy may affect patients with severe schistosomiasis.
Most patients have either Schistosoma japonicum or Schistosoma mansoni
Clinical features:
(1) other evidence of schistosomiasis is common, often hepatosplenomegaly
(2) proteinuria, including nephrotic syndrome
Causes of renal involvement:
(1) immune complex deposition
(2) cryoglobulinemia
Patterns of glomerular involvement include:
(1) membrano-proliferative
(2) mesangial
(3) focal segmental sclerosis
(4) crescentic
