Schamberg purpura is one of the pigmented purpuric eruptions.
It is most commonly diagnosed in adult males but can be seen in women and children.
Clinical features:
(1) nonpalpable purpuric macules and spots. The lesions tend to be located in the legs but can appear elsewhere or be generalized.
(2) pruritic
(3) reddish-brown color (compared to Cayenne pepper)
Some cases have been linked to drug exposure (amlodipine, other).
Histopathology:
(1) low-grade lymphocytic perivasculitis around small blood vessels in the superficial dermis. This has been referred to as a capillaritis.
(2) extravasation of erythrocytes into the interstitium may be present
(3) hemosiderin deposition (explains the brown color seen clinically)
Exclusions:
(1) coagulopathy-related purpura
(2) infectious purpura
