Liu et al reported the SAVE score to evaluate a patient with advanced chronic liver disease. This can help to identify a patient at risk for decompensation who may require more aggressive management. The authors are from multiple institutions in China, Singapore, Japan, Korea, Egypt and India.
Patient selection: cirrhosis
SAVE = stiffness of liver, albumin, varices and platelets
Parameters:
(1) stiffness in kPa
(2) serum albumin in g/L
(3) platelet count in 10^9/L
(4) varices
Parameter
Finding
Points
stiffness in kPa
0.036 * (stiffness)
serum albumin in g/L
-0.152 * (albumin)
platelet count in 10^9/L
-0.011 * (platelet)
varices
absent
0
present
1.177
total score =
= SUM(points for all of the parameters)
Interpretation:
• The higher the score the greater the risk of hepatic decompensation. The risk also increases over time.
Score
Risk
5-Year Decompensation
< -6
low
0%
-6 to -4.5
middle
24.9%
> -4.5
high
69%
Performance:
• The area under the ROC curve is 0.85.
To read more or access our algorithms and calculators, please log in or register.
