A change in a scar, tattoo or other skin lesion may be a manifestation of sarcoidosis.
Lesions that may be affected:
(3) venipuncture site
(4) injection site
(5) site of blunt trauma
The lesions may appear:
(1) erythematous or purple
(3) tender and/or painful
(4) rarely ulcerated
Biopsy of the lesion will show noncaseating granulomas that are negative for acid fast bacilli, fungi and polarizable material.
The patient may have a history of sarcoidosis, or the skin changes may coincide with the initial presentation.
Other manifestations of sarcoidosis may or may not be present:
(1) bilateral hilar adenopathy
(2) pulmonary lesions and/or change in pulmonary function
(3) organ involvement (cardiac, neurologic, etc.)
(4) elevated serum angiotensin converting enzyme (ACE)
(5) elevated serum lysozyme
(1) foreign body granuloma, including suture granuloma
(2) deep fungal or mycobacterial infection
(3) hypertrophic scar or keloid
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Specialty: Dermatology, Immunology/Rheumatology