Pinheiro et al reported the Sao Paulo Osteoporosis Risk Index (SAPORI) to identify a woman with low bone mineral density who is at risk for low-impact bone fractures. Three models were reported - one for low-mineral density in femoral bone, one for low-mineral density in the spine, and one for low-trauma fracture. The authors are from Universidade Federal de Sao Paulo and other institutions in Sao Paulo, Brazil.
Patient selection: pre, peri and postmenopausal women in Sao Paulo with mean age 60.1 years
Parameters:
(1) current hormone replacement therapy
(2) family history of hip fracture
(3) age in years
(4) weight in kilograms
(5) T score in SD
Parameter
Finding
Beta-Coefficient
family history
no
0
yes
1.46
age
0.028 * (age)
T score
>= -2.5 SD
0
< -2.5 SD
0.56
hormone replacement
no
0
yes
-0.38
weight
0.01* (weight)
where:
• The impact of hormone replacement may pertain to postmenopausal women.
value of X =
= SUM(points for all of the beta=coefficients) - 3.19
probability of low-trauma fracture =
= 1 / (1 + EXP((-1) * X))
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