Hapgood et al reported the SALENTO prognostic model for evaluating a patient with limited-stage peripheral T-cell lymphoma (PTCL). The authors are from the International T-Cell Project Network with members from around the world.
Patient selection: age > 18 years, limited-stage PTCL (Stage I or II)
Limited-stage is present in 25-30% of patients.
Parameter:
(1) age in years
(2) serum albumin in g/L
(3) serum LDH in IU/L
Parameter
Finding
Points
age in years
< 60 years
0
>= 60 years
1
serum albumin
< 35 g/L
1
>= 35 g/L
0
serum LDH
<= upper limit of normal
0
> upper limit of normal
1
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 3
Total Score
Risk Group
5-Year Overall Survival
0
low
78%
1
intermediate
46%
2 or 3
high
25%
Performance:
• The area under the ROC curves is 0.69.
Additional factors from univariate analysis:
(1) ECOG performance status 2 to 4
(2) B symptoms
(3) hemoglobin < 120 g/L
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