Compilato et al proposed the Simple-Complex-Destroying (S-C-D) classification system for a patient with a long-standing oral ulcer. The authors are from the University of Palermo, II University of Naples, New York University and University of Foggia.


Patient selection: ulceration not healing withing 2 weeks, classified as destroying or destructive


Causes of rapidly progressive ulcerations:

(1) deep mycosis

(2) noma


Other causes of destructive ulcerations:

(1) syphilis

(2) tuberculosis

(3) actinomycosis

(4) sarcoidosis

(5) deep mycosis

(6) Wegener’s granulomatosis

(7) other vasculitis

(8) squamous cell carcinoma

(9) other malignancy


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