The Rx-Risk Comorbidity Index can be used to evaluate a patient's comorbidities based on the medicatons being taken.
Patient selection: age > 65 years
|
Category |
Weights |
|
alcohol dependency |
6 |
|
allergies |
-1 |
|
anticoagulants |
1 |
|
antiplatelets |
2 |
|
anxiety |
1 |
|
arrhythmia |
2 |
|
benign prostatic hyperplasia |
0 |
|
bipolar disorder |
-1 |
|
chronic airways disease |
2 |
|
congestive heart failure |
2 |
|
dementia |
2 |
|
depression |
2 |
|
diabetes |
2 |
|
epilepsy |
0 |
|
glaucoma |
0 |
|
gastroesophageal reflux |
0 |
|
gout |
1 |
|
HIV |
0 |
|
hyperkalemia |
4 |
|
hyperlipidemia |
-1 |
|
hypertension |
-1 |
|
hyperthyroidism |
2 |
|
hypothyroidism |
0 |
|
irritable bowel syndrome |
0 |
|
ischemic heart disease: angina |
2 |
|
ischemic heart disease: hypertension |
-1 |
|
incontinence |
0 |
|
inflammation/pain |
-1 |
|
liver failure |
3 |
|
malignancies |
2 |
|
malnutrition |
0 |
|
migraine |
-1 |
|
osteoporosis/Paget's |
-1 |
|
pain |
3 |
|
pancreatic insufficiency |
0 |
|
Parkinson's disease |
3 |
|
psoriasis |
0 |
|
psychotic illness |
6 |
|
pulmonary hypertension |
6 |
|
renal disease |
6 |
|
smoking cessation |
6 |
|
steroid-responsive disease |
2 |
|
transplant |
0 |
where:
• The relevant ATC codes are listed in Table 1.
Conditions not graded:
(1) hepatitis B
(2) hepatitis C
(3) tuberculosis
score =
= SUM(points for all 43 drug categories.
Interpretation:
• minimum sum of weights: -8
• maximum sum of weights: 60
• The higher the sum of weights the greater the 1-year mortality.
Performance:
• The area under the ROC curve for the weighted score was 0.79.
