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Rule of Lutgens et al for Risk of Colorectal Carcinoma in a Patient with Inflammatory Bowel Disease (IBD)

Description

Lutgens et al identified risk factors for colorectal cancer in a patient with inflammatory bowel disease. This can help to identify a patient who may benefit from closer surveillance. The authors are from University Medical Center Utrecht, University of California Los Angeles and University Hospital Gasthuisberg in Leuven.


Parameters:

(1) type of inflammatory bowel disease (Crohns vs ulcerative colitis)

(2) primary sclerosing cholangitis (PSC)

(3) extent of disease

(4) post-inflammatory polyps

 

Microscopic Extent of Colonic Surface Involvement

Extent

< 50%

limited

>= 50%

extensive

 

High risk patterns - one or more of the following:

(1) primary sclerosing cholangitis

(2) Crohn's disease AND extensive disease AND post-inflammatory polyps

(3) ulcerative colitis AND (extensive disease AND/OR post-inflammatory polyps)

 

A patient who is not high risk is low risk.


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