Vidyasagar reviewed the NOSEP score of Mahieu et al. He suggested a "rule of 14" to help identify nosocomial sepsis in a neonate in the NICU. The author is from the University of Illinois at Chicago.
Patient selection: newborn infant in the NICU
Rule of 14:
(1) > 14 days of total parenteral nutrition (TPN)
(2) > 14 mg/L serum CRP
(3) <= 140,000 per µL platelet count
(4) > 14 NOSEP score
The presence of a high NOSEP score or several of the other findings identifies a newborn who may have nosocomial sepsis.
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