Roca et al reported the ROX index (Respiratory Rate, Oxygenation) for evaluation of patients receiving high-flow oxygen by nasal cannula. The authors are from multiple institutions in Spain and France.
Parameters:
(1) oxygen saturation from pulse oximetry (SpO2) in percent
(2) FIO2 from 0.21 to 1.0
(3) respiratory rate in breaths per minute
ROX index =
= (SpO2/FIO2) / (respiratory rate) =
= SpO2 / ((FIO2) * (respiratory rate))
Interpretation:
• A ROX index >= 4.88 at 12 hours of high flow therapy indicates a low risk for intubation.
• A patient who does not need intubation tends to show a rising ROX index after high flow oxygen therapy is started.
• An index < 2.85 after 2 hours of high flow oxygen therapy is associated intubation, as is a ROX index < 3.47 at 6 hours and < 3.85 at 12 hours.
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