Infant colic can be diagnosed using the Rome IV criteria.

Patient selection: infant, typically 1 to 4 months old


Diagnostic criteria for infant colic:

(1) age < 5 months when symptoms start and stop

(2) recurrent and prolonged periods of infant crying, fussing and/or irritability

(3) symptoms occur without obvious cause

(4) symptoms cannot be prevented or resolved by caregivers

(5) no other sign of illness (afebrile, etc)


For clinical research symptoms should last for >= 3 hours per day for >= 3 days per week.

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