Functional chest pain can be diagnosed by the Rome IV criteria.
Diagnostic criteria for functional chest pain:
(1) retrosternal chest pain or discomfort
(2) frequency >= 1 time per week
(3) symptom onset >= 6 months prior to diagnosis
(4) present for the past 3 months
(5) exclusion of:
(5a) cardiac cause
(5b) heartburn or dysphagia
(5c) gastroesophageal reflux disease (GERD)
(5d) eosinophilic esophagitis
(5e) esophageal motor disorder
(5f) other causes of chest pain