Hajek et al reported risk scores for a patient with relapsed multiple myeloma. The total risk score is based on the disease aggressiveness risk score and frailty risk scores. The authors are from multiple institutions in Europe.
Patient selection: relapsed multiple myeloma
Parameters for the frailty risk score:
(1) age in years
(2) ECOG performance status
Parameters for total risk score:
(1) disease aggressiveness risk score
(2) frailty risk score
Parameter
Finding
Points
age in years
EXP(0.015 * (age))
ECOG performance
ECOG 0
1
ECOG 1
1.667
ECOG 2
2.123
ECOG 3 and ECOG 4
3.708
frailty risk score =
= PRODUCT(points for both parameters)
total risk score =
= (disease aggressiveness risk score) * (frailty risk score)
Total Risk Score
Group
<= 3
3.01 to 7
2
7.01 to 15.4
3
> 15.4
4
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