Priori et al identified risk factors for patients with the Long QT Syndrome. This can help identify patients who may require closer monitoring and more aggressive therapy. The authors are from University of Pavia in Italy.
Parameters:
(1) gender of the patient
(2) corrected QT interval (QTc)
(3) mutation locus (LQT1, LQT2, LQT3)
|
Gender |
QTc |
Locus |
Risk Group |
|
male |
< 500 msec |
LQT1 |
low |
|
|
< 500 msec |
LQT2 |
low |
|
|
< 500 msec |
LQT3 |
intermediate |
|
|
>= 500 msec |
LQT1 |
high |
|
|
>= 500 msec |
LQT2 |
high |
|
|
>= 500 msec |
LQT3 |
high |
|
female |
< 500 msec |
LQT1 |
low |
|
|
< 500 msec |
LQT2 |
intermediate |
|
|
< 500 msec |
LQT3 |
intermediate |
|
|
>= 500 msec |
LQT1 |
high |
|
|
>= 500 msec |
LQT2 |
high |
|
|
>= 500 msec |
LQT3 |
intermediate |
after Figure 4, page 1872
|
Risk Group |
Probability of First Cardiac Event Before Age 40 and Before Therapy |
|
low |
< 30% |
|
intermediate |
30 – 49% |
|
high |
>= 50% |
where:
• Cardiac event = syncope, cardiac arrest or sudden death.
Specialty: Cardiology
