Schmoeckel et al identified various risk groups associated with malignant melanoma. The authors are from the University of Munich.
Parameters:
(1) tumor thickness in mm
(2) mitotic index (mitoses per square mm using high power magnification)
(3) diameter in cm
(4) prognostic index of Day et al
(5) clinical features (regression, ulceration, unequivocal vascular invasion)
prognostic index =
= (thickness in mm) * (mitotic index)
|
Thickness in mm |
Mitotic Index |
Diameter in cm |
Prognostic Index |
Clinical |
Risk Group |
|
<= 0.75 mm |
< 10 |
<= 3 |
NA |
none |
low |
|
NA |
NA |
NA |
>= 13 |
NA |
high |
|
>= 3.0 mm |
NA |
NA |
NA |
ulcerated |
high |
|
NA |
>= 25 |
NA |
NA |
NA |
very high |
|
NA |
NA |
NA |
NA |
vascular invasion |
very high |
|
NA |
NA |
NA |
NA |
palmar, plantar, subungual |
very high |
A tumor that is does not fit into any of these categories is medium risk.
|
Risk Group |
Rate of Recurrence |
|
low |
< 8% |
|
medium |
30% |
|
high |
65% |
|
very high |
95% |
Specialty: Hematology Oncology, Surgery, general, Dermatology
