Risk Stratification of Baorto et al for a Pediatric Patient with Febrile Neutropenia Using the Absolute Monocyte Count (AMC)

 

Outcomes: bacteremia. Severe cases involved admission to the ICU and/or death.

 

Patient selection: pediatric patient > 12 months old with febrile neutropenia (absolute neutrophil count < 500 per µL at presentation) following chemotherapy. Temperature was >= 38°C taken orally or at the axilla.

 

All patients were treated with parenteral antibiotics at presentation.

 

absolute monocyte count per µL =

= (percent monocytes) * (WBC count per µL) / 100

 

absolute phagocyte count per µL =

= ((percent neutrophils) + (percent monocytes)) * (WBC counter per µL) / 100

Absolute Monocyte Count	Risk Group
>= 250 per µL	very low risk
155 to 249 per µL	low risk
30 to 155	increased risk
< 30 per µL	highest risk

 

Patients with an absolute monocyte count >= 150 per µL are potential candidates for outpatient management.