Wind et al used 2 ratios to stratify the risk for pre-eclampsia in a patient. This can help to identify a patient who may require more aggressive management. The authors are from Leiden University in the Netherlands.
Patient selection: pregnant woman with possible pre-eclampsia
Parameters:
(1) sFLT-1 (solutble FMS-like tyrosine kinase 1) in pg/mL
(2) PlGF (placental growth factor) in pg/mL
(3) urine protein in mg/L
(4) urine creatinine in mmol/L
sFlt-1 to PlGF ratio =
= (sFlt-1) / (PlGF)
urine protein to creatinine ratio =
= (urine protein) / (urine creatinine)
sFlt-1 to PlGF Ratio
Urine P to Cr Ratio
Risk Pre-Eclampsia
<= 38
< 30
1.6%
> 38
< 30
25.5%
<= 38 mg/mmol
>= 30 mg/mmol
26.7%
> 38 mg/mmol
>= 30 mg/mmol
92.3%
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