Zinganell et al reported a model for predicting osteoporosis in a patient with multiple sclerosis. The authors are from the Medical University of Innsbruck.
Patient selection: multiple sclerosis
Parameters:
(1) current smoker
(2) body mass index (BMI) in kg per square meter
(3) age and gender
(4) EDSS score
Parameter
Finding
Points
current smoker
no
0
yes
0.833
BMI
-0.267 * (BMI)
age and sex
male <= 45 years
1.739
male > 45 years
1.922
female premenopausal
0
female postmenopausal
2.594
EDSS
0.293 * (EDSS)
value of X =
= SUM(points for all of the parameters) + 2.893
probability of osteoporosis =
= 1 / (1 + EXP((-1) * X))
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