Risk Score of Xiong et al for Severe Fever with Thrombocytopenia Syndrome (SFTS)

Description

Xiong et al developed a score for predicting mortality in a patient with the severe fever with thrombocytopenia syndrome (SFTS). There is a spectrum of disease severity including multi-organ failure with high mortality. The authors are from Huazhong University and Union Hospital in Wuhan, China.

Severe fever with thrombocytopenia syndrome (SFTS) is a tick-borne (Haemaphysalis longicornis) viral infection caused by a Phlebovirus of the Bunyavirus family.

Outcome: in-hospital mortality

Parameters:

(1) neurologic symptoms level

(2) respiratory symptoms level

(3) viral load in copies/mL

(4) percent monocytes from 0 to 100

Parameter	Findings	Points
respiratory symptoms	none	0
	(cough AND sputum) OR rales	1
	(sputum AND rales) OR (wheezing)	2
	dyspnea OR (extensive rales OR wheezing)	3
neurologic symptoms	none	0
	limb tremor OR confusion OR slow reactions	1
	drowsiness OR frequent muscle contraction	2
	coma	3

total score =

= (5 * (points for neurologic findings)) + (4 * (points for respiratory symptoms)) + (3 * LOG10(viral load)) - (2 * LN(percent monocytes)) - 7

Total Score	Hospital Mortality
<= 7	2%
8 to 15	15%
16 to 23	70%
>=24	100%

Performance:

• The area under the ROC curve is 0.96.

To read more or access our algorithms and calculators, please log in or register.

Risk Score of Xiong et al for Severe Fever with Thrombocytopenia Syndrome (SFTS)

Description

Specialty