Rodrigues et al reported a score for predicting the risk of cerebral amyloid angiopathy (CAA) in a patient with intracerebral hemorrhage (ICH). The authors are from the University of Edinburgh, Newcastle University, University of Southampton, Universite Lille and affiliated hospitals.
Patient selection: intracerebral hemorrhage (ICH)
Parameters:
(1) APOE epsiolon 4 status
(2) subarachnoid hemorrhage (SAH)
(3) finger-like projections from hematoma seen on brain MRI
Parameter
Finding
Points
APOE epsilon 4
negative
0
positive
3.11
subarachnoid hemorrhage
no
0
yes
2.31
finger-like projections
no
0
yes
3.20
risk score =
= SUM(points for all of the parameters) - 2.55
probability of cerebral amyloid angiopathy =
= 1 / (1 + EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.92.
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