Peralta et al developed a score for identifying a patient occult renal dysfunction detectable by serum cystatin C testing. The authors are from the San Francisco Veterans Affairs Medical Center.
Patient selection: 45 to 98 years with eGFR by serum creatinine >= 60 mL per min per 1.73 sq m
Parameters:
(1) age in years
(2) eGFR creatinine in mL per min per 1.73 square meter
(3) diabetes mellitus
(4) hypertension
(5) cardiovascular disease
(6) body mass index (kilograms per square meter)
(7) race and current smoking
|
Parameter |
Finding |
Points |
|
age in years |
45 to 49 years |
0 |
|
|
50 to 59 years |
1 |
|
|
60 to 69 years |
3 |
|
|
70 to 79 years |
6 |
|
|
80 to 89 years |
9 |
|
|
90 to 98 years |
11 |
|
eGFR |
60 to 69 |
14 |
|
|
70 to 74 |
12 |
|
|
75 to 89 |
8 |
|
|
90 to 99 |
4 |
|
|
100 to 110 |
2 |
|
|
> 110 |
0 |
|
diabetes |
absent |
0 |
|
|
present |
1 |
|
hypertension |
absent |
0 |
|
|
present |
1 |
|
cardiovascular disease |
absent |
0 |
|
|
present |
1 |
|
body mass index |
< 22 |
0 |
|
|
22 to 29 |
1 |
|
|
30 to 39 |
3 |
|
|
>= 40 |
8 |
|
current smoking and race |
Black smoker |
2 |
|
|
White smoker |
3 |
|
|
other |
0 |
total score =
= SUM(points for all 7 parameters)
Interpretation:
• minimum score: 0
• maximum score: 39
• The higher the score the greater the chance that occult
|
Total Score |
Percent |
|
< 5 |
< 0.5% |
|
5 to 12.5 |
(0.036 * ((score)^2)) + (0.038 * (score)) - 0.545 |
|
12.5 to 25 |
(0.2457 * ((score)^2)) - (4.381 * (score)) + 21.9 |
|
22.5 to 32.5 |
(-0.2629 * ((score)^2)) + (19.3 * (score)) - 253.6 |
|
> 32.5 |
> 96% |
Specialty: Nephrology, Clinical Laboratory
