Description

Liu et al reported a simple score and nomogram to identify a cholestatic patient with biliary atresia. The authors are from Capital Medical University, Shanghai Medical College, and First Medical University of Shandong in China.


Patient selection: infants with cholestasis (ages 6 to 12 weeks)

 

Parameters:

(1) clay stool

(2) gallbladder emptying index (GEI)

(3) shear wave elastography in kPa

(4) serum GGT in IU/L

 

Parameter

Finding

Points

clay stool

no

0

 

yes

1

gallbladder emptying index

normal

0

q

abnormal

1

shear wave elastography

<= 10 kPa

0

 

> 10 kPa

1

serum GGT

<=200 IU/L

0

 

201 to 300 IU/L

1

 

> 300 IU/L

2

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 5

 

Total Score

Risk Category

Risk of Biliary Atresia

0 or 1

low

<= 10%

2 or 3

intermediate

37-80%

4 or 5

high

98-100%

 

Performance:

• The authors claim an area under the ROC curve os 0.97.


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