Risk Score of Gao et al for Contrast-Induced Nephropathy (CIN) After Cardiac Catheterization in Chinese Patients

Description

Gao et al developed a score for identifying a Chinese patient at risk for contrast-induced nephropathy (CIN) after cardiac catheterization. This can help to identify a patient who may benefit from more aggressive management or an alternative to contrast. The authors are from Beijing Anzhen Hospital and Capital Medical University in Beijing.

Patient selection: Chinese patient undergoing cardiac catheterization

Definition CIN: increase in serum creatinine >= 44.2 µmol/L or >= 25%; above the upper limit of the reference range; within 72 hours of the procedure

Parameters:

(1) age in years

(2) hypertension

(3) acute myocardial infarction

(4) heart failure

(5) use of an intra-aortic balloon pump (IABP)

(6) baseline eGFR in mL per min per 1.73 sq m

(7) contrast volume in mL

Parameter	Finding	Points
age in years	<= 60 years	0
	> 60 years	2
hypertension	no	0
	yes	2
acute myocardial infarction	no	0
	yes	2
heart failure	no	0
	yes	2
use of IABP	no	0
	yes	4
baseline eGFR	>= 90	0
	70 to 89	1
	50 to 69	2
	30 to 49	3
	< 30	6
contrast volume	<= 100 mL	0
	101 to 300 mL	1
	> 300 mL	3

total score =

= SUM(points for all 7 parameters)

Interpretation:

• minimum score: 0

• maximum score: 21

• The higher the score the greater the risk for contrast-induced nephropathy.

Score	Risk Group	Percent CIN
0 to 4	low	1.2%
5 to 8	moderate	6.3%
9 to 11	high	16.8%
>= 12	very high	27.3%

Performance:

• The area under the ROC curve was 0.76 for the derivation set and 0.71 for the validation set.

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Risk Score of Gao et al for Contrast-Induced Nephropathy (CIN) After Cardiac Catheterization in Chinese Patients

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