Description

Fu et al developed a score for predicting the risk of contrast-induced nephropathy in an older adult undergoing percutaneous coronary intervention (PCI). This can help to identify a patient who may benefit from more aggressive management or an alternative to contrast. The authors are from Tianjin Chest Hospital and Tianjin Medical University in China.


Patient selection: older adult (>= 65 years) undergoing PCI with contrast (low-osmolar or iso-osmolar)

 

Parameters:

(1) eGFR in mL per min per 1.73 square meter

(2) left ventricular ejection fraction (LVEF) in percent

(3) diabetes

(4) hypotension

(5) anemia

(6) age in years

(7) emergency procedure

(8) acute myocardial infarction

(9) contrast volume in mL

 

Parameter

Finding

beta-coefficient

Points

eGFR

>= 60

0

0

 

< 60

1.215

4

LVEF

>= 45%

0

0

 

< 45%

0.937

3

diabetes

no

0

0

 

yes

1.029

3

hypotension

no

0

0

 

yes

1.009

2

anemia

no

0

0

 

yes

0.801

2

age in years

65 to 70

0

0

 

> 70

0.577

2

emergency

no

0

0

 

yes

0.862

2

AMI

no

0

0

 

yes

0.817

2

contrast volume

<= 200 mL

0

0

 

> 200 mL

0.789

2

 

total score =

= SUM(points for all 9 parameters)

 

X =

= SUM(points for all 9 beta-coefficients) - 4.307

 

probability =

= 1 / (1 + EXP(-1)*X))

 

Interpretation:

minimum score: 0

maximum score: 22

The higher the score the greater the risk of contrast-induced nephropathy.

 

Score

Percent Nephropathy

0

1.5%

2

2%

3

5%

4

7%

5

9%

6

10%

7

13%

8

13%

9

27%

10

27%

11

39%

12

52%

13

57%

14

66%

>= 15

84%

from Figure 1

 

Performance:

The area under the ROC curve is 0.79.


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