Description

Conrad et al developed a model for predicting long-term survival for an asymptomatic patient undergoing a carotid endarterectomy. This can help to decide if the procedure is appropriate for a patient. The authors are from the Massachusetts General Hospital.


 

Patient selection: asymptomatic carotid artery disease

 

Parameters:

(1) age in years

(2) coronary artery disease

(3) statin therapy

(4) diabetes mellitus

(5) history of neck irradiation

(6) COPD

(7) serum creatinine in mg/dL

Parameter

Finding

Points

age in years

< 50 years of age

0

 

50 to 59 years of age

2

 

60 to 69 years of age

4

 

70 to 79 years of age

6

 

80 to 89 years of age

8

 

>= 90 years of age

10

coronary artery disease

no

0

 

yes

2

statin therapy

no

2

 

yes

0

diabetes mellitus

no

0

 

yes

2

neck irradiation

no

0

 

yes

3

COPD

no

0

 

yes

3

serum creatinine

<= 1.5 mg/dL

0

 

> 1.5 mg/dL

3

 

total score =

= SUM(points for all 7 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 25

• The higher the score the worse the long-term survival.

• A patient with good long-term survival is likely to benefit from CEA while a patient with poor long-term survival may benefit from medical management.

 

Total Score

5-Year Survival

0 to 5

93%

6 to 8

84%

9 to 11

64%

12 to 14

47%

15 to 25

34%

 

Performance:

• The area under the ROC curve was 0.74.

 


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