Massicotte-Azarniouch et al reported the risk of venous thromboembolism in patients based on estimated glomerular filtration rate and level of albuminuria. The authors are from multiple institutions in Canada.
Parameters:
(1) eGFR
(2) urinary albumin to creatinine ratio (ACR) in mg per gram
Table of Hazard Ratios
eGFR
ACR < 30
ACR 30-300
ACR > 300
>= 90
1
1.29
1.61
60 to 89
1.19
1.38
1.55
45 to 59
1.35
1.40
1.41
30 to 44
1.40
1.30
1.36
15 to 29
1.23
1.20
1.09
The greatest risk is seen with a eGFR > 90 mL/min/1.73 square meters and albuminuria (albumin to creatinine ratio > 300 mg per gram creatinine).
Often the risk is combined with risk from other comorbidities and medications.
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