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Risk of Recurrence for Down's Syndrome in the Offspring of a Woman with a Previously Affected Infant

Purpose:

To predict the risk of recurrence of Down's syndrome for a woman who has had a previously affected pregnancy.

Specialty:

Genetics

Objective:

risk factors, severity, prognosis, stage

ICD-10:

Description:

The risk of recurrence for Down's syndrome in a pregnancy following one previously affected can be estimated based on the age of the woman and the genetic abnormality, as described by Donnai (1988). The risk of recurrence is low if the mother is young and if the affected gestation showed trisomy 21.

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