Yeo et al reported a score for predicting intracerebral hemorrhage (ICH) following the use of intravenous tissue plasminogen activator (tPA) in an Asian stroke patient. The authors are from National University Health System Singapore, Chang Gung University and affiliated hospitals in Taiwan.
Patient selection: adult Asian patient status post stroke, following infusion of tissue plasminogen activator (tPA)
Parameters:
(1) age in years
(2) NIHSS in the ER
(3) blood glucose in mg/dL
(4) atrial fibrillation
Parameters
Findings
Points
age in years
25
0
35
1
45
2
60
3
70
4
80
5
95
6
NIHSS
0
0
5
10
10
20
15
30
20
40
30
61
35
71
40
81
blood glucose
50
0
100
11
150
22
200
33
250
44
300
56
350
67
400
78
450
89
500
100
atrial fibrillation
no
0
yes
34
total score =
= SUM(points for all 4 parameters)
Interpretation:
• minimum score: 0
• maximum score: 221
value of X =
= (0.02451 * (score)) - 3.344
probability of intracerebral hemorrhage =
= 1 / (1 + EXP((-1) *X))
Performance:
• The area under the ROC curve is 0.66.
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