Mahmood et al developed a clinical risk score for predicting the need of intraoperative blood transfusion in a patient undergoing endovascular aneurysm repair. This can help to identify a patient who is likely to need transfusion prior to the surgery. The authors are from Northwestern University, the University of Chicago and Beth Israel Deaconess Medical Center.
Patient selection: endovascular aneurysm repair of an abdominal aortic aneurysm
Outcome: intraoperative blood transfusion
Parameters:
(1) ASA classification
(2) hemoglobin concentration in g/dL
(3) diameter of the aneurysm in mm
(4) age of the patient in years
Parameter |
Finding |
Points |
ASA class |
ASA 1 |
1 |
|
ASA 2 |
2 |
|
ASA 3 |
3 |
|
ASA 4 |
4 |
|
ASA 5 |
5 |
hemoglobin |
> 14.5 g/dL |
1 |
|
13.6 to 14.5 |
2 |
|
12.3 to 13.5 |
3 |
|
< 12.3 |
4 |
diameter of the aneurysm |
< 52 mm |
1 |
|
52 to 55 mm |
2 |
|
56 to 60 mm |
3 |
|
> 60 mm |
4 |
age in years |
< 69 years |
1 |
|
70 to 75 years |
2 |
|
76 to 81 years |
3 |
|
> 81 years |
4 |
total score =
= SUM(points for all 4 parameters)
Interpretation:
• minimum score: 4
• maximum score: 17
• The higher the score the more likely that the patient will need to be transfused.
If the actual outcome in Figure 1 is analyzed:
Score |
Percent Transfused |
4 |
0 |
5 |
0 |
6 |
1% |
7 |
2% |
8 |
2.5% |
9 |
3% |
10 |
4% |
11 |
6% |
12 |
8% |
13 |
10% |
14 |
12% |
15 |
21% |
16 |
31% |
17 |
68% |
Performance:
• The scoring indicates that the risk increase per step is linear, which is arguable for ASA class and aneurysm diameter. This may explain the deviation in Figure 1.
• The area under the ROC curve was 0.73 for the derivation set.
Specialty: Clinical Laboratory, Surgery, general