medical decision support medical decision support
Sign In

Risk Factors of Wylie et al for Central Line Associated Bloodstream Infection (CLABSI) in a Pediatric Patient in the Intensive Care Unit (ICU)

Description

Wylie et al evaluated patients in a pediatric ICU who developed central line associated bloodstream infections (CLABSI). They identified risk factors for CLABSI. The authors are from Children's Hospital Boston and Harvard Medical School.


Patient selection: in pediatric ICU (a few adults included)

 

Outcome: CLABSI

 

Risk factors for CLABSI:

(1) parenteral nutrition (odds ratio 3.1)

(2) transfusion of packed red blood cells (odds ratio 2.6)

(3) gastrostomy tube (odds ratio 3.5)

(4) duration of ICU central catheter (odds ratio 14.7 for 4 to 14 days and 18.4 for >= 15 days)

(5) number of central lines placed in the ICU (odds ratio 8.6 for 2 or more and 2.4 for 1)

(6) combination of cardiovascular disease and no surgery (odds ratio 7.4)

(7) combination of cardiovascular disease and surgery (odds ratio 2.2)

 

cumulative product of odds ratios =

= PRODUCT(odds ratios for all of the parameters)

 

Interpretation:

• minimum cumulative product: 1

• maximum cumulative product: 33,033

• The greater the cumulative product the greater the risk of CLABSI.


To read more or access our algorithms and calculators, please log in or register.

Specialty