Major arterial thrombotic complications:
(1) angina pectoris
(2) myocardial infarction
(3) transient ischemic attacks
(4) cerebrovascular accidents
(5) peripheral arterial occlusion
Major venous thrombotic complications:
(1) pulmonary embolism
(2) deep vein thromboiss
(3) portal vein thrombosis
(4) hepatic vein thrombosis
(5) splenic vein thrombosis
(6) mesenteric vein thrombosis
The cumulative probability of a major thrombosis by at 5 years is 32%.
The cumulative probability at 20 years is 52%.
Parameters:
(1) age
(2) history of arterial thrombosis
(3) white blood cell count at diagnosis
|
Parameter
|
Findings
|
Points
|
|
age in years
|
< 60 years
|
0
|
|
|
>= 60 years
|
1
|
|
history of arterial thrombosis
|
none
|
0
|
|
|
present
|
1
|
|
WBC count at diagnosis
|
< 15,000 per µL
|
0
|
|
|
>= 15,000 per µL
|
1
|
number of risk factors for thrombotic complications =
= SUM(points for the 3 risk factors)
Interpretation:
• minimum number of risk factors: 0
• maximum number of risk factors: 3
• The risk of thrombotic complications increases with the number of risk factors.
