Risk Factors of Verlut et al for Poor Overall Survival for a Patient with Glioblastoma Multiforme Receiving Chemoradiotherapy

 

Patient selection: glioblastoma treated with chemoradiotherapy

 

Outcome: overall survival

 

Parameters:

(1) age in years

(2) MRC neurologic scale (from 0 to 4)

(3) complications following surgery (biopsy or resection)

Parameter	Finding	Points
age in years	<= 65 years	0
	> 65 years	1
MRC neurologic scale	0, 1 or 2	0
	3 or 4	1
complications after surgery	absent	0
	present	1

 

number of risk factors for a poor outcome =

= SUM(points for the 3 risk factors)

 

Interpretation:

• minimum number of risk factors: 0

• maximum number of risk factors: 3

• The risk of a poor overall survival increases with the number of risk factors.