Description

Uebing et al identified common risk factors in a pregnant woman with congenital heart disease that can have significant adverse effects on the fetus. These can help identify a woman who should have a careful evaluation of the fetus during the pregnancy. The authors are from the Imperial College and Chelsea and Westminster Hospital in London.


 

Parameters:

(1) New York Heart Association functional status

(2) cyanosis

(3) left heart outflow obstruction

(4) maternal age

(5) cigarette smoking

(6) anticoagulant therapy

(7) systemic hypertension

(8) beta-blocker therapy

Parameters

Findings

Points

NYHA functional class

I or II

0

 

III or IV

1

cyanosis

absent

0

 

present

1

left heart outflow obstruction

absent

0

 

present

1

maternal age

< 20 years

1

 

20 - 35 years

0

 

> 35 years

1

cigarette smoking

none

0

 

present

1

anticoagulant therapy

absent

0

 

present

1

systemic hypertension

absent

0

 

present

1

beta-blocker therapy

absent

0

 

present

1

 

where:

• Left heart outflow obstruction may include (a) mitral valve area < 2 square cm, (b) aortic valve area < 1.5 square cm, (c) left ventricular outflow tract peak blood pressure gradient before pregnancy > 30 mm Hg

 

Other risk factors not listed:

(1) ethanol abuse

(2) cocaine, methamphetamine or other drug abuse

(3) gestational diabetes

 

number of risk factors for adverse fetal effects =

= SUM(points for all of the parameters)

 

Interpretation:

• A woman with one or more risk factors should have close monitoring during the pregnancy with regular fetal assessments.

 


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