Trinh et al reported a number of risk factors for multidrug-resistant Pseudomonas aeruginosa causing pneumonia in patients in the intensive care unit (ICU). These can help to identify a patient who may require careful selection of antibiotics and more aggressive management. The authors are from Wayne State University and Henry Ford Health System.

Patient selection: ICU patient with Pseudomonas aeruginosa pneumonia, excluding cystic fibrosis


Independent risk factors:

(1) >= 24 hours of antibiotic (carbapenems, fluoroquinolones, piperacillin-tazobactam) therapy in preceding 90 days

(2) nursing home residence


Other factors that may contribute:

(1) comorbid conditions

(2) Pseudomonas aeruginosa colonization

(3) exposure to more than 1 class of antipseudomonal antibiotics

(4) hospitalization >= 48 hours in preceding 90 days

(5) colonization with Pseudomonas aeruginosa

(6) mechanical ventilation

To read more or access our algorithms and calculators, please log in or register.