Su et al identified risk factors associated with hypothyroidism following hemithyroidectomy. These factors can help to identify a patient who may require closer monitoring over time. The authors are from Monash Medical Centre and The Alfred Hospital in Melbourne, Australia.

Patient selection: hemithyroidectomy with preoperative serum TSH <= 4 mIU/L (upper limit of normal reference range)


Outcome: hypothyroidism (occurred in about 11% of patients)


Risk factors for hypothyroidism:

(1) preoperative serum TSH that is high-normal (2.5 to 4.0 mIU/L)

(2) histologic evidence of chronic thyroiditis

(3) elevated serum antithyroid antibodies (anti-thyroid peroxidase, anti-thyroglobulin)



• The normal reference range was 0.5 to 4.0 mIU/L with mean 2.3


Patients should be monitored for hypothyroidism after hemithyroidectomy but this should be more frequent if the patient has one or more risk factors.

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